Leukotrienes in Tumor-Associated Inflammation

Leukotrienes are biologically active eicosanoid lipid mediators that originate from oxidative metabolism of arachidonic acid. Biosynthesis of leukotrienes involves a set of soluble and membrane-bound enzymes that constitute a machinery complex primarily expressed by cells of myeloid origin. Leukotri...

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Bibliographic Details
Main Authors: Wen Tian, Xinguo Jiang, Dongeon Kim, Torrey Guan, Mark R. Nicolls, Stanley G. Rockson
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Pharmacology
Subjects:
cancer
leukotrienes
inflammation
tumor microenvironment
LTB4
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01289/full
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