ANTIMICROBIAL ACTIVITY STUDY OF NEW QUINAZOLIN-4(3H)-ONES AGAINST STAPHYLOCOCCUS AUREUS AND STREPTOCOCCUS PNEUMONIAE

Quinazolin-4(3H)-one derivatives exhibiting a wide spectrum of a pharmacological activity, represent a promising class of substances used to obtain antibacterial agents, which is especially important in the context of the emergence of pathogenic microorganisms’ resistance to drugs used in medicine....

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Main Authors: M. A. Samotrueva, A. A. Ozerov, A. A. Starikova, N. M. Gabitova, D. V. Merezhkina, A. A. Tsibizova, I. N. Tyurenkov
Formato: Artigo
Idioma:Russo
Publicado em: Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical University 2021-09-01
Colecção:Farmaciâ i Farmakologiâ (Pâtigorsk)
Assuntos:
quinazolinone derivatives
antimicrobial activity
lead-compound
electron-donating centers
enzyme active site
minimum inhibitory concentration
minimum suppressing concentration
bacteriostatic action
bactericidal activity
resistance
atp-dependent efflux pump
plasmids
transposones
large mobile element
Acesso em linha:https://www.pharmpharm.ru/jour/article/view/885
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