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Mitochondrion-mediated iron accumulation promotes carcinogenesis and Warburg effect through reactive oxygen species in osteosarcoma

Abstract Background Iron metabolism disorder is closely associated with several malignant tumors, however the mechanisms underlying iron and the carcinogenesis in osteosarcoma are not yet well understood. Methods Cell proliferation ability of osteosarcoma cell lines was measured by CCK-8, EdU incorp...

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Библиографические подробности
Главные авторы: Shuo Ni, Yanbin Kuang, Yin Yuan, Baoqing Yu
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2020-08-01
Серии:Cancer Cell International
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Online-ссылка:http://link.springer.com/article/10.1186/s12935-020-01494-3
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