F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa

The metabolite 2-methoxyestradiol (2ME) is an endogenous estrogen metabolite with potential therapeutic properties in reproductive cancers. However, the molecular mechanisms by which 2ME exerts its anticancer activity are not well elucidated. The purpose of this study was to determine the molecular...

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Autori principali: Ramiro Rincón-Rodriguez, Dennise Mena, Javier Mena, Patricia Díaz-Saldivar, Emanuel Guajardo-Correa, Carlos Godoy-Guzman, Hugo Cardenas, Pedro A. Orihuela
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-08-01
Serie:International Journal of Molecular Sciences
Soggetti:
cancer
2-methoxyestradiol
F-spondin
Ishikawa cells
apoptosis
Accesso online:https://www.mdpi.com/1422-0067/20/16/3850
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