Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways.

Cigarette smoking is a common addiction that increases the risk for many diseases, including lung cancer and chronic obstructive pulmonary disease. Genome-wide association studies (GWAS) have successfully identified and validated several susceptibility loci for nicotine consumption and dependence. H...

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Hauptverfasser: Oscar Harari, Jen-Chyong Wang, Kathleen Bucholz, Howard J Edenberg, Andrew Heath, Nicholas G Martin, Michele L Pergadia, Grant Montgomery, Andrew Schrage, Laura J Bierut, Pamela F Madden, Alison M Goate
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC3515482?pdf=render
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