Identifying key genes and functionally enriched pathways in Th2-high asthma by weighted gene co-expression network analysis

Abstract Background Asthma is a chronic lung disease characterized by reversible inflammation of the airways. The imbalance of Th1/Th2 cells plays a significant role in the mechanisms of asthma. The aim of this study was to identify asthma-related key genes and functionally enriched pathways in a Th...

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Hauptverfasser: Yao Cao, Yi Wu, Li Lin, Lin Yang, Xin Peng, Lina Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2022-05-01
Schriftenreihe:BMC Medical Genomics
Schlagworte:
Asthma
Weighted gene coexpression network analysis (WGCNA)
Hub gene
Gene ontology
Online Zugang:https://doi.org/10.1186/s12920-022-01241-9
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