Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression

Multiple myeloma (MM) has two clinical precursor stages of disease: monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM). However, the mechanism of progression is not well understood. Because gene co-expression network analysis is a well-known method for di...

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Main Authors: Christina Y. Yu, Shunian Xiang, Zhi Huang, Travis S. Johnson, Xiaohui Zhan, Zhi Han, Mohammad Abu Zaid, Kun Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-05-01
Colecção:Frontiers in Genetics
Assuntos:
multiple myeloma
MGUS
SMM
gene co-expression
copy number variation
Acesso em linha:https://www.frontiersin.org/article/10.3389/fgene.2019.00468/full
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