Glycolysis and Oxidative Phosphorylation Play Critical Roles in Natural Killer Cell Receptor-Mediated Natural Killer Cell Functions

Natural killer (NK) cells are innate lymphocytes that directly kill tumor and pathogen-infected cells upon activation by cytokines and NK cell receptors (NKRs) without previous sensitization. It is known that cell metabolism affects the differentiation and effector functions of immune cells. For ins...

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Bibliografische gegevens
Hoofdauteurs: Zixi Wang, Di Guan, Shu Wang, Louis Yi Ann Chai, Shengli Xu, Kong-Peng Lam
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020-02-01
Reeks:Frontiers in Immunology
Onderwerpen:
natural killer cells
anti-tumor
cell metabolism
glycolysis
CD16
NKG2D
Online toegang:https://www.frontiersin.org/article/10.3389/fimmu.2020.00202/full
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