Tumor Microenvironment Cascade-Responsive Nanodrug with Self-Targeting Activation and ROS Regeneration for Synergistic Oxidation-Chemotherapy

Abstract Carrier-free nanodrug with exceptionally high drug payload has attracted increasing attentions. Herein, we construct a pH/ROS cascade-responsive nanodrug which could achieve tumor acidity-triggered targeting activation followed by circularly amplified ROS-triggered drug release via positive...

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Detalhes bibliográficos
Main Authors: Yang Li, Jinyan Lin, Peiyuan Wang, Qiang Luo, Fukai Zhu, Yun Zhang, Zhenqing Hou, Xiaolong Liu, Jingfeng Liu
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2020-09-01
Colecção:Nano-Micro Letters
Assuntos:
Targeting activation
Positive-feedback loop
Circular amplification of ROS
Vitamin E nanodrug
Synergistic oxidation-chemotherapy
Acesso em linha:http://link.springer.com/article/10.1007/s40820-020-00492-4
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