CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma

Osteosarcoma, the most common of all bone malignancies, has a high likelihood of lung metastasis. Up until now, the molecular mechanisms involved in osteosarcomas with lung metastases are not clearly understood. Recent observations have shown that the chemokine CXCL1 and its receptor CXCR2 assist wi...

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Bibliographic Details
Main Authors: Chia-Chia Chao, Chiang-Wen Lee, Tsung-Ming Chang, Po-Chun Chen, Ju-Fang Liu
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
osteosarcoma
cxcl1
cxcr2
migration
vcam-1
Online Access:https://www.mdpi.com/2072-6694/12/2/459
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