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Alterations of epigenetic signatures in hepatocyte nuclear factor 4α deficient mouse liver determined by improved ChIP-qPCR and (h)MeDIP-qPCR assays.

Hepatocyte nuclear factor 4α (HNF4α) is a liver-enriched transcription factor essential for liver development and function. In hepatocytes, HNF4α regulates a large number of genes important for nutrient/xenobiotic metabolism and cell differentiation and proliferation. Currently, little is known abou...

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Bibliografski detalji
Glavni autori: Qinghao Zhang, Xiaohong Lei, Hong Lu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2014-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3888413?pdf=render
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