Upregulation of prostaglandin E by inducible microsomal prostaglandin E synthase-1 in colon cancer

Purpose Prostaglandin E2 (PGE2) is known to promote carcinogenesis and cancer progression in colon cancer. Enzymes involved in the metabolism of PGE2 include cyclooxygenase (COX)-2, microsomal prostaglandin E synthase-1 (mPGES-1), and 15-prostaglandin dehydrogenase (15-PGDH). The current study aims...

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Autors principals: Young Hun Kim, Kyung Jong Kim
Format: Artigo
Idioma:Inglês
Publicat: Korean Society of Coloproctology 2022-04-01
Col·lecció:Annals of Coloproctology
Matèries:
colonic neoplasms
dinoprostone
prostaglandin-e synthases
cyclooxygenase 2
15-hydroxyprostaglandin dehydrogenase
Accés en línia:http://coloproctol.org/upload/pdf/ac-2021-00374-0053.pdf
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