The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial.

The rate of acquisition of naturally acquired immunity (NAI) against malaria predominantly depends on transmission intensity and age, although disentangling the effects of these is difficult. We used chemoprophylaxis to selectively control exposure to P. falciparum during different periods in infanc...

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Autori principali: Caterina Guinovart, Carlota Dobaño, Quique Bassat, Augusto Nhabomba, Llorenç Quintó, Maria Nélia Manaca, Ruth Aguilar, Mauricio H Rodríguez, Arnoldo Barbosa, John J Aponte, Alfredo G Mayor, Montse Renom, Cinta Moraleda, David J Roberts, Evelin Schwarzer, Peter N Le Souëf, Louis Schofield, Chetan E Chitnis, Denise L Doolan, Pedro L Alonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3296698?pdf=render
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