Hydroxysafflor Yellow A Exerts Anti-Inflammatory Effects Mediated by SIRT1 in Lipopolysaccharide-Induced Microglia Activation

Abnormal microglia activation causes sever neuroinflammation, contributing to the development of many diseases, yet the mechanism remains incompletely unknown. In current study, we identified that Hydroxysafflor yellow A (HYA), a chalcone glycoside derived from Carthamus tinctorius L effectively att...

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Detalhes bibliográficos
Main Authors: Xiude Qin, Juanjuan Chen, Guowei Zhang, Chuanpeng Li, Jinqiang Zhu, Hong Xue, Jinfang Li, Tianxiang Guan, Haotao Zheng, Yu Liu, Haobin Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-09-01
Colecção:Frontiers in Pharmacology
Assuntos:
hydroxysafflor yellow A
anti-inflammatory
lipopolysaccharide
SIRT1
microglia
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2020.01315/full
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