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Identification of bifurcation transitions in biological regulatory networks using Answer-Set Programming

Abstract Background Numerous cellular differentiation processes can be captured using discrete qualitative models of biological regulatory networks. These models describe the temporal evolution of the state of the network subject to different competing transitions, potentially leading the system to...

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Autors principals: Louis Fippo Fitime, Olivier Roux, Carito Guziolowski, Loïc Paulevé
Format: Artigo
Idioma:Inglês
Publicat: BMC 2017-07-01
Col·lecció:Algorithms for Molecular Biology
Accés en línia:http://link.springer.com/article/10.1186/s13015-017-0110-3
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