Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE<sup>−/−</sup> Mouse Model

Vascular smooth muscle cells (VSMCs) can switch from their contractile state to a synthetic phenotype resulting in high migratory and proliferative capacity and driving atherosclerotic lesion formation. The cysteine-rich LIM-only protein 4 (CRP4) reportedly modulates VSM-like transcriptional signatu...

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Main Authors: Natalie Längst, Julia Adler, Anna Kuret, Andreas Peter, Peter Ruth, Karsten Boldt, Robert Lukowski
格式: Artigo
語言:Inglês
出版: MDPI AG 2022-04-01
叢編:Cells
主題:
acyl-CoA dehydrogenase long chain (ACADL)
apolipoprotein E (ApoE)
3′,5′-cyclic guanosine monophosphate (cGMP)
3′,5′-cyclic guanosine monophosphate-dependent protein kinase type I (cGKI)
cysteine-rich LIM-only protein 4 (CRP4)
microtubule associated monooxygenase
在線閱讀:https://www.mdpi.com/2073-4409/11/8/1364
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