Synaptic loss in a mouse model of euthyroid Hashimoto’s thyroiditis: possible involvement of the microglia

Abstract Background Hashimoto’s thyroiditis (HT) is an autoimmune illness that renders individuals vulnerable to neuropsychopathology even in the euthyroid state, the mechanisms involved remain unclear. We hypothesized that activated microglia might disrupt synapses, resulting in cognitive disturban...

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Bibliografische gegevens
Hoofdauteurs: Fen Wang, Yao-Jun Cai, Xiao Ma, Nan Wang, Zhang-Bi Wu, Yan Sun, Yong-xia Xu, Hao Yang, Tian-tian Liu, Qin Xia, Zhen Yu, De-Fa Zhu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2022-04-01
Reeks:BMC Neuroscience
Onderwerpen:
Hashimoto’s thyroiditis
Rodent model
Synaptic loss
Microglia
Phagocytosis
Online toegang:https://doi.org/10.1186/s12868-022-00710-2
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