Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia.

Glioblastoma is the most malignant and lethal form of astrocytoma, with patients having a median survival time of approximately 15 months with current therapeutic modalities. It is therefore important to identify novel therapeutics. There is mounting evidence that microglia (specialized brain-reside...

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Hlavní autoři: Ian S Miller, Sebastien Didier, David W Murray, Tia H Turner, Magimairajan Issaivanan, Rosamaria Ruggieri, Yousef Al-Abed, Marc Symons
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC4015930?pdf=render
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