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High Glucose Concentration Impairs 5-PAHSA Activity by Inhibiting AMP-Activated Protein Kinase Activation and Promoting Nuclear Factor-Kappa-B-Mediated Inflammation

Recently, the endogenous fatty acid palmitic acid-5-hydroxystearic acid (5-PAHSA) was found to increase insulin sensitivity and have anti-inflammatory effects in mice with high-fat diet (HFD)-induced diabetes. However, it is unknown if 5-PAHSA affects glucose and lipid metabolism in db/db mice, whic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yan-Mei Wang, Hong-Xia Liu, Ning-Yuan Fang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2019-01-01
Cyfres:Frontiers in Pharmacology
Pynciau:
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fphar.2018.01491/full
Tagiau: Ychwanegu Tag
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