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The baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis.
Accurate estimates of mutation rates provide critical information to analyze genome evolution and organism fitness. We used whole-genome DNA sequencing, pulse-field gel electrophoresis, and comparative genome hybridization to determine mutation rates in diploid vegetative and meiotic mutation accumu...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2010-09-01
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| Colecção: | PLoS Genetics |
| Acesso em linha: | http://europepmc.org/articles/PMC2936533?pdf=render |
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