Kidney Injury Molecule-1 is Elevated in Nephropathy and Mediates Macrophage Activation via the Mapk Signalling Pathway

Background/Aims: Kidney injury molecule-1 (KIM-1) is highly expressed in renal tubular cells after injury and is usually regarded as an early biomarker of acute kidney injury(AKI). The aim of this study was to determine the role of KIM-1 in the development of renal tubular injury Methods: Clinical s...

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Autori principali: Lei Tian, Xinghua Shao, Yuanyuan Xie, Qin Wang, Xiajing Che, Minfang Zhang, Weijia Xu, Yao Xu, Shan Mou, Zhaohui Ni
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Physiol Biochem Press GmbH & Co KG 2017-02-01
Serie:Cellular Physiology and Biochemistry
Soggetti:
Kidney injury molecule-1
Macrophage
MAPK signaling pathway
Acute kidney injury
Chronic kidney disease
Accesso online:http://www.karger.com/Article/FullText/458737
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