Evidence showing lipotoxicity worsens outcomes in covid-19 patients and insights about the underlying mechanisms

Summary: We compared three hospitalized patient cohorts and conducted mechanistic studies to determine if lipotoxicity worsens COVID-19. Cohort-1 (n = 30) compared COVID-19 patients dismissed home to those requiring intensive-care unit (ICU) transfer. Cohort-2 (n = 116) compared critically ill ICU p...

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Bibliographic Details
Main Authors: Rodrigo Cartin-Ceba, Biswajit Khatua, Bara El-Kurdi, Shubham Trivedi, Sergiy Kostenko, Zaid Imam, Ryan Smith, Christine Snozek, Sarah Navina, Vijeta Sharma, Bryce McFayden, Filip Ionescu, Eugene Stolow, Sylvia Keiser, Aziz Tejani, Allison Harrington, Phillip Acosta, Saatchi Kuwelker, Juan Echavarria, Girish B. Nair, Adam Bataineh, Vijay P. Singh
Format: Artigo
Language:Inglês
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
health sciences
virology
medical microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222005934
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