Attenuation of UVB-Induced Photo-Aging by Polyphenolic-Rich Spatholobus Suberectus Stem Extract Via Modulation of MAPK/AP-1/MMPs Signaling in Human Keratinocytes

It is well known that ultraviolet light activates mitogen-activated protein (MAP) kinase by increasing the reactive oxygen species (ROS) in the body, enhancing activating protein 1(AP-1) complexes (c-Jun and c-Fos), increasing matrix metalloproteinases (MMPs) and degrading collagen and elastin. In t...

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Main Authors: Kyoo-Ri Kwon, Md Badrul Alam, Ji-Hyun Park, Tae-Ho Kim, Sang-Han Lee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-06-01
Colecção:Nutrients
Assuntos:
anti-aging
<i>Spatholobus suberectus</i>
matrix metalloproteinases (MMPs)
collagen type I alpha 1 (COL1A1)
elastin (ELN)
mitogen-activated protein kinase (MAPK)
Acesso em linha:https://www.mdpi.com/2072-6643/11/6/1341
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