Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet

Cancer metabolism is characterized by extensive glucose consumption through aerobic glycolysis. No effective therapy exploiting this cancer trait has emerged so far, in part, due to the substantial side effects of the investigated drugs. In this study, we examined the side effects of a combination o...

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Bibliographic Details
Main Authors: Martin Voss, Nadja I. Lorenz, Anna-Luisa Luger, Joachim P. Steinbach, Johannes Rieger, Michael W. Ronellenfitsch
Format: Artigo
Language:Inglês
Published: MDPI AG 2018-08-01
Series:International Journal of Molecular Sciences
Subjects:
2-deoxyglucose (2-DG)
isocaloric ketogenic diet
glycolysis
Warburg effect
metabolic cancer therapy
Online Access:http://www.mdpi.com/1422-0067/19/8/2462
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