Endoplasmic Reticulum Stress-Induced Resistance to Doxorubicin Is Reversed by Mulberry Leaf Polyphenol Extract in Hepatocellular Carcinoma through Inhibition of COX-2

Mulberry (<i>Morus alba</i> L.) leaves are used in Chinese medicine to treat metabolic disorders. Mulberry leaf polyphenol extracts (MLPE) have recently been shown to exhibit anticancer properties. Endoplasmic reticulum (ER) stress represents a pivotal obstacle in solid tumors, resulting...

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Main Authors: Mon-Yuan Yang, Cheng-Hsun Wu, Tung-Wei Hung, Chau-Jong Wang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-12-01
Colecção:Antioxidants
Assuntos:
mulberry leaves
er stress
drug resistance
hepatocellular carcinoma
mulberry leaf polyphenol extract
Acesso em linha:https://www.mdpi.com/2076-3921/9/1/26
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