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Identification of novel antifungal agents: antimicrobial evaluation, SAR, ADME–Tox and molecular docking studies of a series of imidazole derivatives
Abstract Thirty-four imidazole-based compounds synthesized by one-pot catalytic method were evaluated for their antifungal and antibacterial activities against several fungal and bacterial strains. None of the compounds had antibacterial activity. Interestingly, compounds 1, 2, 3, 10 and 15 displaye...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
BMC
2019-08-01
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Series: | BMC Chemistry |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13065-019-0623-6 |
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