Pharmacogenomics of soft tissue sarcomas: New horizons to understand efficacy and toxicity

Clinical responses to anticancer therapies in advanced soft tissue sarcoma (STS) are unfortunately limited to a small subset of patients. Much of the inter-individual variability in treatment efficacy and risk of toxicities is as result of polymorphisms in genes encoding proteins involved in drug ph...

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Detalhes bibliográficos
Main Authors: Elisabetta Gambale, Anna Boddi, Adriano Pasqui, Domenico Andrea Campanacci, Guido Scoccianti, Ilaria Palchetti, Andrea Bernini, Lorenzo Antonuzzo, Serena Pillozzi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:Cancer Treatment and Research Communications
Assuntos:
Soft tissue sarcoma
Cancer pharmacogenetic
Pharmacogenomics
Single-nucleotide polymorphisms
Toxicity
Biomarker
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2468294222000193
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