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Differential Enzymatic Activity of Rat ADAR2 Splicing Variants Is Due to Altered Capability to Interact with RNA in the Deaminase Domain

In mammals, adenosine (A) to inosine (I) RNA editing is performed by adenosine deaminases acting on RNA (ADAR), ADAR1 and ADAR2 enzymes, encoded by mRNAs that might undergo splicing process. In rat, two splicing events produce several isoforms of ADAR2, called ADAR2a, ADAR2b, ADAR2e, and ADAR2f, but...

詳細記述

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書誌詳細
主要な著者: Alice Filippini, Daniela Bonini, Edoardo Giacopuzzi, Luca La Via, Fabrizio Gangemi, Marina Colombi, Alessandro Barbon
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2018-02-01
シリーズ:Genes
主題:
オンライン・アクセス:http://www.mdpi.com/2073-4425/9/2/79
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