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The putative tumor suppressor VILIP-1 counteracts epidermal growth factor-induced epidermal-mesenchymal transition in squamous carcinoma cells.

Epithelial-mesenchymal transition (EMT) is a crucial step for the acquisition of invasive properties of carcinoma cells during tumor progression. Epidermal growth factor (EGF)-treatment of squamous cell carcinoma (SCC) cells provokes changes in the expression of lineage markers, morphological change...

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Auteurs principaux: Katharina Schönrath, Andres J Klein-Szanto, Karl H Braunewell
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2012-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3316558?pdf=render
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