Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.

Malignant pleural mesothelioma is a highly chemoresistant solid tumor. We have studied this apoptotic resistance using in vitro and ex vivo three-dimensional models, which acquire a high level of chemoresistance that can be reduced by PI3K/mTOR inhibitors. Here, we investigate the activity of GDC-09...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Dario Barbone, Carlo Follo, Nohemy Echeverry, Victor H Gerbaudo, Astero Klabatsa, Raphael Bueno, Emanuela Felley-Bosco, V Courtney Broaddus
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4540424?pdf=render
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki