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Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.

Malignant pleural mesothelioma is a highly chemoresistant solid tumor. We have studied this apoptotic resistance using in vitro and ex vivo three-dimensional models, which acquire a high level of chemoresistance that can be reduced by PI3K/mTOR inhibitors. Here, we investigate the activity of GDC-09...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dario Barbone, Carlo Follo, Nohemy Echeverry, Victor H Gerbaudo, Astero Klabatsa, Raphael Bueno, Emanuela Felley-Bosco, V Courtney Broaddus
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2015-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC4540424?pdf=render
תגים: הוספת תג
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