Exosomes derived from mesenchymal stem cells enhance radiotherapy-induced cell death in tumor and metastatic tumor foci

Abstract Background We have recently shown that radiotherapy may not only be a successful local and regional treatment but, when combined with MSCs, may also be a novel systemic cancer therapy. This study aimed to investigate the role of exosomes derived from irradiated MSCs in the delay of tumor gr...

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Detalhes bibliográficos
Main Authors: Virgínea de Araujo Farias, Francisco O’Valle, Santiago Serrano-Saenz, Per Anderson, Eduardo Andrés, Jesús López-Peñalver, Isabel Tovar, Ana Nieto, Ana Santos, Francisco Martín, José Expósito, F. Javier Oliver, José Mariano Ruiz de Almodóvar
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-08-01
Colecção:Molecular Cancer
Assuntos:
Experimental radiotherapy
Bystander effect
Abscopal effect
Mesenchymal stem cells
Cell therapy
Metastasis spread
Acesso em linha:http://link.springer.com/article/10.1186/s12943-018-0867-0
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