Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

Current sources of platelets for transfusion are insufficient and associated with risk of alloimmunization and blood-borne infection. These limitations could be addressed by the generation of autologous megakaryocytes (MKs) derived in vitro from somatic cells with the ability to engraft and differen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Julian Pulecio, Oriol Alejo-Valle, Sandra Capellera-Garcia, Marianna Vitaloni, Paula Rio, Eva Mejía-Ramírez, Ilaria Caserta, Juan A. Bueren, Johan Flygare, Angel Raya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2016-10-01
Cyfres:Cell Reports
Pynciau:
transdifferentiation
lineage conversion
Fanconi anemia
thrombocytopenia
platelets
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S221112471631275X
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