Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

Current sources of platelets for transfusion are insufficient and associated with risk of alloimmunization and blood-borne infection. These limitations could be addressed by the generation of autologous megakaryocytes (MKs) derived in vitro from somatic cells with the ability to engraft and differen...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Julian Pulecio, Oriol Alejo-Valle, Sandra Capellera-Garcia, Marianna Vitaloni, Paula Rio, Eva Mejía-Ramírez, Ilaria Caserta, Juan A. Bueren, Johan Flygare, Angel Raya
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016-10-01
Col·lecció:Cell Reports
Matèries:
transdifferentiation
lineage conversion
Fanconi anemia
thrombocytopenia
platelets
Accés en línia:http://www.sciencedirect.com/science/article/pii/S221112471631275X
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars