Single-cell profiling of human dura and meningioma reveals cellular meningeal landscape and insights into meningioma immune response

Abstract Background Recent investigations of the meninges have highlighted the importance of the dura layer in central nervous system immune surveillance beyond a purely structural role. However, our understanding of the meninges largely stems from the use of pre-clinical models rather than human sa...

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Main Authors: Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Genome Medicine
Assuntos:
Single-cell RNA sequencing
Dura
Meninges
Imaging mass cytometry
Acesso em linha:https://doi.org/10.1186/s13073-022-01051-9
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