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Cyclosporine A alters expression of renal microRNAs: New insights into calcineurin inhibitor nephrotoxicity.

Calcineurin inhibitors are powerful immunosuppressants that revolutionized organ transplantation. However, non-immune effects of the calcineurin inhibitor, such as cyclosporine A (CsA), have significantly hindered their use. Specifically, nephrotoxicity, which is associated with tubulointerstitial f...

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Main Authors: Jennifer L Gooch, Clayton King, Cynthia E Francis, Paul S Garcia, Yun Bai
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2017-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC5393575?pdf=render
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