GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse

Abstract Background The sperm protein IZUMO1 (Izumo sperm-egg fusion 1) and its recently identified binding partner on the oolemma, IZUMO1R, are among the first ligand-receptor pairs shown to be essential for gamete recognition and adhesion. However, the IZUMO1-IZUMO1R interaction does not appear to...

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Autori principali: Avinash S. Gaikwad, Amanda L. Anderson, D. Jo Merriner, Anne E. O’Connor, Brendan J. Houston, R. John Aitken, Moira K. O’Bryan, Brett Nixon
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2019-10-01
Serie:BMC Biology
Soggetti:
Spermatozoa
Fertilization
Capacitation
IZUMO
GLIPR1L1
Oolemma
Accesso online:http://link.springer.com/article/10.1186/s12915-019-0701-1
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