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Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion

Adipogenesis, or the conversion of proliferating preadipocytes into nondividing adipocytes, is an important part of the vertebrate weight-maintenance program. It is not yet understood how and when an irreversible transition occurs into a distinct state capable of accumulating lipid. Here, we use sin...

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Main Authors: Byung Ouk Park, Robert Ahrends, Mary N. Teruel
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2012-10-01
Sraith:Cell Reports
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S2211124712002793
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