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Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion

Adipogenesis, or the conversion of proliferating preadipocytes into nondividing adipocytes, is an important part of the vertebrate weight-maintenance program. It is not yet understood how and when an irreversible transition occurs into a distinct state capable of accumulating lipid. Here, we use sin...

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Bibliografiske detaljer
Main Authors: Byung Ouk Park, Robert Ahrends, Mary N. Teruel
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2012-10-01
Serier:Cell Reports
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124712002793
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