Chemopreventive Effect of Dietary Glutamineon Colitis-Associated Colorectal Cancer Is Associated with Modulation of the DEPTOR/mTOR Signaling Pathway

Glutamine plays a protective role in colitis and colitis-associated colorectal cancer (CAC); however, the protective mechanisms are largely unknown to date. DEP domain-containing mTOR-interacting protein (DEPTOR)/mammalian Target of Rapamycin (mTOR) signaling plays an important role in carcinogenesi...

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Hlavní autoři: Yun Tian, Keming Wang, Yingrui Fan, Yan Wang, Liqun Sun, Li Wang, Jirong Wang, Zhaoxia Wang, Juan Li, Ying Ye, Guozhong Ji
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2016-05-01
Edice:Nutrients
Témata:
colitis
colorectal cancer
glutamine
DEPTOR
mTOR signaling
On-line přístup:http://www.mdpi.com/2072-6643/8/5/261
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