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Infusion Reactions Associated with the Medical Application of Monoclonal Antibodies: The Role of Complement Activation and Possibility of Inhibition by Factor H

Human application of monoclonal antibodies (mAbs), enzymes, as well as contrast media and many other particulate drugs and agents referred to as “nanomedicines”, can initiate pseudoallergic hypersensitivity reactions, also known as infusion reactions. These may in part be mediated by the activation...

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Detalhes bibliográficos
Main Authors: Tamás Fülöp, Tamás Mészáros, Gergely Tibor Kozma, János Szebeni, Mihály Józsi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-03-01
Colecção:Antibodies
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Acesso em linha:http://www.mdpi.com/2073-4468/7/1/14
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