β-Glucan Combined With PD-1/PD-L1 Checkpoint Blockade for Immunotherapy in Patients With Advanced Cancer

Programmed death-1 (PD-1)/PD-ligand 1 (PD-L1) checkpoint blocking antibodies have been shown to be a powerful immune checkpoint blockade (ICB) therapy for patients with cancer. However, patients quickly develop resistance to immunotherapy. β-glucan, an immune adjuvant, has been found to stimulate in...

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Autori principali: Mengjie Wang, Yu Bai, Jiaxin Pei, Dongqing Li, Xiaolin Pu, Wenyu Zhu, Lei Xia, Chunjian Qi, Hua Jiang, Yongling Ning
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-04-01
Serie:Frontiers in Pharmacology
Soggetti:
β-Glucan
PD-1
PD-L1
immune checkpoint blockade therapy
resistance
Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2022.887457/full
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