Captopril, a Renin–Angiotensin System Inhibitor, Attenuates Tumour Progression in the Regenerating Liver Following Partial Hepatectomy

(1) Liver regeneration following partial hepatectomy for colorectal liver metastasis (CRLM) has been linked to tumour recurrence. Inhibition of the renin–angiotensin system (RASi) attenuates CRLM growth in the non-regenerating liver. This study investigates whether RASi exerts an antitumour effect w...

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Detalhes bibliográficos
Main Authors: Georgina E. Riddiough, Katrina A. Walsh, Theodora Fifis, Georgios Kastrappis, Bang M. Tran, Elizabeth Vincan, Vijayaragavan Muralidharan, Christopher Christophi, Claire L. Gordon, Marcos V. Perini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-05-01
Colecção:International Journal of Molecular Sciences
Assuntos:
surgical oncology
liver regeneration
immunology
hepatic tissue-resident memory T cells
liver neoplasms
neoplasm metastasis
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/5281
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