Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice

<p>Abstract</p> <p>Background</p> <p>CpG oligodeoxynucleotides (CpG-ODN) are capable of inducing high amounts of type I IFNs with many immunomodulatory properties. Furthermore, type-I IFNs have been proposed to play a key role in mediating effects of CpG-ODN. The precis...

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Hlavní autoři: Navikas Vaidrius, Teige Ingrid, Treschow Alexandra, Matheu Victor, Issazadeh-Navikas Shohreh
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2005-03-01
Edice:Respiratory Research
Témata:
IFN-β
CpG motifs
allergy
asthma
inflammation
synovitis
arthritis
eosinophil
IFN-γ
Th1-response
knockout
lung
On-line přístup:http://respiratory-research.com/content/6/1/25
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