Feasibility assessment of in vitro chemoresponse assay on stereotactic biopsies of glioblastoma multiforms: a step towards personalized medicine

Objective(s):P In vitro chemosensitivity and resistance assays (CSRAs) are a promising tool for personalized treatment of glioblastoma multiform (GBM). These assays require a minimum of 1 to 2 g of tumor specimen for testing, but this amount is not always accessible. We aimed to assess the feasibili...

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Main Authors: Fariba Sadeghi Fazel, Mahnaz Haddadi, Alireza Khoshnevisan, Samad Muhammadnejad, Ahad Muhammadnejad, Zohreh Mazaheri, Motahareh Arjomandnejad, Reza Shirkoohi, Mohammad-Ali Oghabian, Narjes Sherkat-Khameneh, Saeid Amanpour, Monireh Kazemimanesh
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2014-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Glioblastomamultiform In vitro chemosensitivity and resistance assay Personalized medicine Primary explant technique Stereotactic biopsy
Online Access:http://ijbms.mums.ac.ir/pdf_3747_18889a2b2c356f4ab92fad027b03e2be.html
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