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Data-Driven Mathematical Model of Apoptosis Regulation in Memory Plasma Cells

Memory plasma cells constitutively produce copious amounts of antibodies, imposing a critical risk factor for autoimmune disease. We previously found that plasma cell survival requires secreted factors such as APRIL and direct contact to stromal cells, which act in concert to activate NF-κB- and PI3...

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主要な著者: Philipp Burt, Rebecca Cornelis, Gustav Geißler, Stefanie Hahne, Andreas Radbruch, Hyun-Dong Chang, Kevin Thurley
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2022-05-01
シリーズ:Cells
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オンライン・アクセス:https://www.mdpi.com/2073-4409/11/9/1547
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