Curcumin attenuates collagen-induced inflammatory response through the “gut-brain axis”

Abstract Background Previous studies have demonstrated that oral administration of curcumin exhibited an anti-arthritic effect despite its poor bioavailability. The present study aimed to explore whether the gut-brain axis is involved in the therapeutic effect of curcumin. Methods The collagen-induc...

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Hauptverfasser: Yannong Dou, Jinque Luo, Xin Wu, Zhifeng Wei, Bei Tong, Juntao Yu, Ting Wang, Xinyu Zhang, Yan Yang, Xusheng Yuan, Peng Zhao, Yufeng Xia, Huijuan Hu, Yue Dai
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-01-01
Schriftenreihe:Journal of Neuroinflammation
Schlagworte:
Curcumin
Collagen-induced arthritis
Gut-brain axis
Unilateral cervical vagotomy
α7 nAChR
Nodose ganglion neurons
Online Zugang:http://link.springer.com/article/10.1186/s12974-017-1047-7
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