Efficient Strategies for Microglia Replacement in the Central Nervous System

Summary: Microglia are important immune cells in the central nervous system (CNS). Dysfunctions of gene-deficient microglia contribute to the development and progression of multiple CNS diseases. Microglia replacement by nonself cells has been proposed to treat microglia-associated disorders. Howeve...

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Detalhes bibliográficos
Main Authors: Zhen Xu, Yanxia Rao, Yubin Huang, Tian Zhou, Rui Feng, Shanshan Xiong, Ti-Fei Yuan, Shan Qin, Yijie Lu, Xin Zhou, Xiaoyu Li, Bo Qin, Ying Mao, Bo Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-08-01
Colecção:Cell Reports
Assuntos:
microglia
replacement
repopulation
CSF1R
fate mapping
parabiosis
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124720310263
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