MicroRNA-9 Fine-Tunes Dendritic Cell Function by Suppressing Negative Regulators in a Cell-Type-Specific Manner

Summary: Dendritic cells, cells of the innate immune system, are found in a steady state poised to respond to activating stimuli. Once stimulated, they rapidly undergo dynamic changes in gene expression to adopt an activated phenotype capable of stimulating immune responses. We find that the microRN...

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Main Authors: Brendan Cordeiro, Peter Jeon, Giselle M. Boukhaled, Mario Corrado, Orsolya Lapohos, Dominic G. Roy, Kelsey Williams, Russell G. Jones, Samantha Gruenheid, Selena M. Sagan, Connie M. Krawczyk
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2020-05-01
Sraith:Cell Reports
Ábhair:
dendritic cells
microRNA
miR-9
PCGF6
transcriptional regulators
tumor
Rochtain Ar Líne:http://www.sciencedirect.com/science/article/pii/S2211124720305349
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