Histone Modification of Embryonic Stem Cells Produced by Somatic Cell Nuclear Transfer and Fertilized Blastocysts

Objective: Nuclear transfer-embryonic stem cells (NT-ESCs) are genetically identical to the donor’s cells; provide a renewable source of tissue for replacement, and therefore, decrease the risk of immune rejection. Trichostatin A (TSA) as a histone deacetylase inhibitor (HDACi) plays an important ro...

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Autori principali: Fattaneh Farifteh, Mohammad Salehi, Mojgan Bandehpour, Nariman Mosaffa, Marefat Ghafari Novin, Taher Hosseini, Sedigheh Nematollahi, Mohsen Noroozian, Somayeh Keshavarzi, Ahmad Hosseini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royan Institute (ACECR), Tehran 2013-01-01
Serie:Cell Journal
Soggetti:
Somatic Cell Nuclear Transfer
Trichostatin A
Epigenetics Modification
Accesso online:http://celljournal.org/library/upload/article/af_82322236227653456223336424353357374233546-Farifteh-1.pdf
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